The new wide openers couldn't compete with The Social Network [SOCIL], which stayed in first place with an estimated $15.5 million. The Facebook movie declined just 31% in its second weekend.
Life As We Know It [LAWKI] debuted at $14.6 million for the second spot while Secretariat [SCTRT] showed in third place at $12.6 million.
| Rank | TITLE | F-S-S | TOTAL |
| 1 | THE SOCIAL NETWORK | $15,500,000 | $46,069,000 |
| 2 | LIFE AS WE KNOW IT | $14,635,000 | $14,635,000 |
| 3 | SECRETARIAT | $12,600,000 | $12,600,000 |
| 4 | LEGEND OF THE GUARDIANS: THE OWLS OF GA'HOOLE | $7,015,000 | $39,401,000 |
| 5 | MY SOUL TO TAKE | $6,918,680 | $6,918,680 |
| 6 | THE TOWN | $6,350,000 | $73,787,000 |
| 7 | WALL STREET: MONEY NEVER SLEEPS | $4,625,000 | $43,666,578 |
| 8 | EASY A | $4,200,000 | $48,139,000 |
| 9 | CASE 39 | $2,630,000 | $9,600,000 |
| 10 | YOU AGAIN | $2,474,000 | $20,731,000 |
| 11 | LET ME IN | $2,400,000 | $9,123,801 |
| 12 | IT'S KIND OF A FUNNY STORY | $2,011,982 | $2,011,982 |
Source: Exhibitor Relations Co.