Delivering the second best 3-day opening for the franchise after 2007's Spider-Man 3, Spider-Man: Homecoming [SPID6] netted an estimated $117.0 million to top the weekend box office. The webslinger attracted an audience that was 60% male and 50% under the age of 25.
Despciable Me 3 [DESM3] stepped down to second with $34.0 million, down 53% from its debut. The total stans at $149.2 million.
Baby Driver [BDRIV] finished third with $12.8 million. The music-driven actioner declined 38% in its second weekend to bring its total to $56.9 million.
Transformers: The Last Knight [TFRM5] earned $6.3 million to take the fifth spot. The sequel has banked $118.9 million after three weeks.
Cars 3 [CARS3] added $5.6 million in its fourth weekend to advance to $133.7 million.
| Rank | TITLE | F-S-S | TOTAL |
| 1 | SPIDER-MAN: HOMECOMING | $117,000,000 | $117,000,000 |
| 2 | DESPICABLE ME 3 | $33,998,000 | $149,189,000 |
| 3 | BABY DRIVER | $12,750,000 | $56,880,000 |
| 4 | WONDER WOMAN | $10,135,000 | $368,786,000 |
| 5 | TRANSFORMERS: THE LAST KNIGHT | $6,300,000 | $118,917,000 |
| 6 | CARS 3 | $5,636,000 | $133,733,000 |
| 7 | THE HOUSE | $4,815,000 | $18,631,000 |
| 8 | THE BIG SICK | $3,650,000 | $6,920,323 |
| 9 | 47 METERS DOWN | $2,768,400 | $38,462,000 |
| 10 | THE BEGUILED | $2,086,000 | $7,435,000 |
| 11 | PIRATES OF THE CARIBBEAN: DEAD MEN TELL NO TALES | $1,200,000 | $168,825,000 |
| 12 | THE MUMMY | $1,164,000 | $77,974,000 |
Tag(s): SPID6, DESM3, BDRIV, TFRM5, CARS3