Two female targeted films were still no match on Mother's Day weekend as Avengers: Infinity War [AVNG3] led for the third time with an estimated $61.8 million. The Marvel team-up has banked $547.8 million.
Life of the Party [LFOPT] debuted in second place with $18.5 million. The comedy skewed 70% female and 80% over the age of 25.
Breaking In [BRKIN] took in $16.5 million to open at the third spot. The audience was 65% female and 73% over the age of 25.
Overboard [OVERB] declined just 31% in its second weekend to $10.1 million and fourth overall. The comedy remake has earned $29.6 million.
Tully [TULLY] finished eighth with $2.2 million, off 32% from its opening weekend.
| Rank | TITLE | F-S-S | TOTAL |
| 1 | AVENGERS: INFINITY WAR | $61,800,000 | $547,829,103 |
| 2 | LIFE OF THE PARTY | $18,500,000 | $18,500,000 |
| 3 | BREAKING IN | $16,500,000 | $16,500,000 |
| 4 | OVERBOARD | $10,100,000 | $29,594,000 |
| 5 | A QUIET PLACE | $6,400,000 | $169,553,000 |
| 6 | I FEEL PRETTY | $3,710,000 | $43,850,000 |
| 7 | RAMPAGE | $3,380,000 | $89,745,000 |
| 8 | TULLY | $2,240,000 | $6,980,060 |
| 9 | BLACK PANTHER | $1,932,000 | $696,186,611 |
| 10 | RBG | $1,165,000 | $2,002,000 |
| 11 | BLOCKERS | $1,130,000 | $58,140,635 |
| 12 | ISLE OF DOGS | $1,050,000 | $29,929,000 |
Tag(s): AVNG3, LFOPT, BRKIN, OVERB, TULLY