Reviving the box office after a dead August and blowing past all expectations, It [IT1] consumed an estimated $117.2 million. The debut sets new records for largest opening for September, fall and horror genre. The audience was 51% female and 65% over the age of 25.
Home Again [HMAGN] opened in second place with $9.0 million.
The Hitman's Bodyguard [HTMBG] finished third at $4.9 million, bringing its total to $64.9 million.
Wind River [WNDRV] took fifth place with $3.2 million and $25.0 million overall.
| Rank | TITLE | F-S-S | TOTAL |
| 1 | IT | $117,150,000 | $117,150,000 |
| 2 | HOME AGAIN | $9,028,222 | $9,028,222 |
| 3 | THE HITMAN'S BODYGUARD | $4,850,000 | $64,897,007 |
| 4 | ANNABELLE: CREATION | $4,000,000 | $96,267,000 |
| 5 | WIND RIVER | $3,210,200 | $25,002,192 |
| 6 | LEAP! | $2,500,100 | $15,874,536 |
| 7 | SPIDER-MAN: HOMECOMING | $2,015,000 | $327,702,000 |
| 8 | DUNKIRK | $1,950,000 | $183,110,000 |
| 9 | LOGAN LUCKY | $1,826,425 | $25,372,002 |
| 10 | THE EMOJI MOVIE | $1,060,000 | $82,516,000 |
| 11 | DESPICABLE ME 3 | $909,000 | $259,958,000 |
| 12 | GIRLS TRIP | $802,000 | $113,360,000 |
Tag(s): IT1, HMAGN, HTMBG, WNDRV