Debuting with an estimated $61.5 million at the weekend box office, Mission: Impossible - Fallout [MISS6] scored the biggest franchise opening, surpassing Mission: Impossible II's $57.4 million in 2000. The audience was 55% male compared to 62% for the previous installment, Rogue Nation.
Mamma Mia! Here We Go Again [MAMI2] remained in second place with $15.0 million. The musical sequel declined 57% in its sophomore session to bring its total to $70.4 million.
Last weekend's champ, The Equalizer 2 [EQLZ2] dropped 61% to $14 million and the third spot. The action sequel has banked $64.2 million.
Hotel Transylvania: Summer Vacation [HTRN3] finished fourth at $12.3 million for a total of $119.2 million.
Teen Titans Go! To the Movies [TNTNG] admitted just $10.5 million to debut fifth overall. The cartoon proved to be frontloaded by its fans.
| Rank | TITLE | F-S-S | TOTAL |
| 1 | MISSION: IMPOSSIBLE - FALLOUT | $61,500,000 | $61,500,000 |
| 2 | MAMMA MIA! HERE WE GO AGAIN | $15,000,000 | $70,424,525 |
| 3 | THE EQUALIZER 2 | $14,000,000 | $64,231,345 |
| 4 | HOTEL TRANSYLVANIA 3: SUMMER VACATION | $12,305,000 | $119,228,501 |
| 5 | TEEN TITANS GO! TO THE MOVIES | $10,510,000 | $10,510,000 |
| 6 | ANT-MAN AND THE WASP | $8,400,000 | $183,124,127 |
| 7 | INCREDIBLES 2 | $7,157,000 | $572,780,648 |
| 8 | JURASSIC WORLD: FALLEN KINGDOM | $6,775,000 | $397,553,500 |
| 9 | SKYSCRAPER | $5,400,000 | $59,149,760 |
| 10 | THE FIRST PURGE | $2,230,000 | $65,483,875 |
| 11 | UNFRIENDED: DARK WEB | $1,500,000 | $7,393,430 |
| 12 | SORRY TO BOTHER YOU | $1,450,000 | $13,351,421 |
Tag(s): MISS6, MAMI2, EQLZ2, HTRN3, TNTNG