Outperforming expectations to become STX's first number one film, The Upside [NTCHB] banked an estimated $19.6 million to lead the weekend box office. The comedy drew 59% female and 74% aged 25 or older.
Aquaman [AQUMN] was dethroned to second with $17.9 million, bringing its sum to $287.9 million after four weekends.
A Dog's Way Home [DOGWH] found $11.3 million to debut at the third spot. The family film appealed to a broad audience that was 52% female and 51% over 25.
Escape Room [TMAZE] finished fifth at $8.9 million, down 51% from its opening. The horror was locked up $32.4 million.
In its first weekend of wide expansion, On the Basis of Sex [OBSEX] jumped up to the eighth slot with $6.2 million.
Replicas [RPLIC] bombed in its twelfth place opening of just $2.5 million.
If Beale Street Could Talk [IBSCT] finished outside the top 12 with $2.4 million in its wide expansion to 1018 theaters.
| Rank | TITLE | F-S-S | TOTAL |
| 1 | THE UPSIDE | $19,590,000 | $19,590,000 |
| 2 | AQUAMAN | $17,265,000 | $287,861,781 |
| 3 | A DOG'S WAY HOME | $11,300,000 | $11,300,000 |
| 4 | SPIDER-MAN: INTO THE SPIDER-VERSE | $9,000,000 | $147,775,445 |
| 5 | ESCAPE ROOM | $8,900,000 | $32,432,931 |
| 6 | MARY POPPINS RETURNS | $7,215,000 | $150,656,985 |
| 7 | BUMBLEBEE | $6,775,000 | $108,470,000 |
| 8 | ON THE BASIS OF SEX | $6,227,000 | $10,558,847 |
| 9 | THE MULE | $5,545,000 | $90,578,000 |
| 10 | VICE | $3,278,644 | $35,936,000 |
| 11 | BOHEMIAN RHAPSODY | $3,200,000 | $198,496,000 |
| 12 | REPLICAS | $2,500,000 | $2,500,000 |
Tag(s): NTCHB, AQUMN, DOGWH, TMAZE, OBSEX, RPLIC, IBSCT